abstract：:The developmental rate of a blastocyst is considered one of the main estimates for evaluating the implantation potential of embryos. Day 6 blastocysts have been reported to be much less viable than day 5 blastocysts. Regarding implantation, the implantation window is advanced due to a background of high sex hormones, ...

journal_title：Reproductive biomedicine online

authors： Murata Y,Oku H,Morimoto Y,Tokuda M,Murata T,Sugihara K,Nagata F,Nakaoka Y,Fukuda A

更新日期：2005-10-01 00:00:00

abstract：:The receptive phase of the endometrium seems to occur in close association with the appearance of pinopodes and endometrial integrins that may be activated by the interleukin-1 system (IL-1). Embryo attachment is the result of adhesion protein expression, and the invasion of the embryo is governed by proteolytic enzym...

journal_title：Reproductive biomedicine online

authors： Bulletti C,Flamigni C,de Ziegler D

更新日期：2005-10-01 00:00:00

abstract：:Construction of artificial gametes may be made possible by transferring somatic cells into enucleated oocytes and inducing chromosomal halving of their nuclei. This study examines the possibility of constructing viable human gametes, and their potential for participation in normal fertilization. Spare germinal vesicle...

journal_title：Reproductive biomedicine online

authors： Takeuchi T,Neri QV,Palermo GD

更新日期：2005-09-01 00:00:00

abstract：:The European Union's Tissues and Cells Directive (2004) establishes an extensive framework of standards for all tissue banks throughout the EU. This article considers how the requirements of the Directive might be expected to achieve the stated goals of promoting the safety of assisted conception treatments and/or fac...

journal_title：Reproductive biomedicine online

authors： Mortimer D

更新日期：2005-08-01 00:00:00

abstract：:The clinical impact of PGD was evaluated through the analysis of the reproductive outcome before and after PGD in the same group of poor prognosis IVF patients, undergoing PGD for chromosomal abnormalities. Based on a series of 2359 PGD cycles, resulting in the establishment of 498 chromosomal abnormality-free clinica...

journal_title：Reproductive biomedicine online

authors： Verlinsky Y,Tur-Kaspa I,Cieslak J,Bernal A,Morris R,Taranissi M,Kaplan B,Kuliev A

更新日期：2005-08-01 00:00:00

abstract：:Human cloning, organ cloning and tissue cloning are various types of cloning that occur at different levels with different methodologies. According to three standards of terminology for an embryo (fertilization through germ cells, development in the uterus and having the potential to produce a human life), tissue clon...

journal_title：Reproductive biomedicine online

authors： Cui KH

更新日期：2005-07-01 00:00:00

abstract：:The outcomes of 1028 assisted reproductive technology cycles were studied retrospectively, considering two different periods of embryo transfer. In the first period, 262 cycles in women < 36 years old were studied, in which three embryos were transferred, followed by 157 cycles in women > or = 36 years, in which four ...

journal_title：Reproductive biomedicine online

authors： Setti PE,Cavagna M,Albani E,Morreale G,Novara PV,Cesana A,Parini V

更新日期：2005-07-01 00:00:00

abstract：:Application of recombinant technology to FSH in the early 1990s produced a highly purified preparation. Calibration of the product was dependent on the rat 'bioassay' based on measurement of ovarian weight after injection of FSH into rats. This test is associated with variability in the measurement of FSH bioactivity ...

journal_title：Reproductive biomedicine online

authors： Hugues JN,Durnerin IC

更新日期：2005-06-01 00:00:00

abstract：:During the early follicular phase in the menstrual cycle, antral follicle sizes are often markedly heterogeneous. These follicular size discrepancies may, at least in part, result from the early exposure of FSH-sensitive follicles to gradient FSH concentrations during the preceding luteal phase. In addition, they pote...

journal_title：Reproductive biomedicine online

authors： Fanchin R,Méndez Lozano DH,Schonäuer LM,Cunha-Filho JS,Frydman R

更新日期：2005-06-01 00:00:00

abstract：:The advent of recombinant gonadotrophins brought significant changes in fertility therapy. Treatment options with recombinant gonadotrophins add more to knowledge on folliculogenesis and ovarian steroidogenesis. Over a decade, recombinant LH (rLH) has been used for clinical trials, and the amount of peripheral LH that...

journal_title：Reproductive biomedicine online

authors： Caglar GS,Asimakopoulos B,Nikolettos N,Diedrich K,Al-Hasani S

更新日期：2005-06-01 00:00:00

abstract：:Several hypotheses have been advanced to explain empty follicle syndrome (EFS) but it remains a controversial topic. This paper reports experience with three IVF cycles in which no oocytes were collected. In all cases, an additional IVF cycle was performed. The ovarian stimulation protocol, ultrasound and hormonal sur...

journal_title：Reproductive biomedicine online

authors： Lorusso F,Depalo R,Tsadilas S,Caradonna F,Di Gilio A,Capotorto MT,Vacca M,Nappi L,Selvaggi L

更新日期：2005-05-01 00:00:00

abstract：:Different gonadotrophin preparations derived from human urine or manufactured by recombinant technology are currently used in clinical practice for the treatment of infertility. It has been widely assumed that gonadotrophin products manufactured by recombinant technology have better batch-to-batch consistency compared...

journal_title：Reproductive biomedicine online

authors： Wolfenson C,Groisman J,Couto AS,Hedenfalk M,Cortvrindt RG,Smitz JE,Jespersen S

更新日期：2005-04-01 00:00:00

abstract：:The aim of the current study was to examine the effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) on the development and differentiation of preimplantation mouse embryos from different strains and under different culture conditions. Embryos from F1 hybrid mice were cultured in a modified G1 medium l...

journal_title：Reproductive biomedicine online

authors： Karagenc L,Lane M,Gardner DK

更新日期：2005-04-01 00:00:00

abstract：:There are many arguments from many sides, which purport to give reasons for limiting access to reproductive technologies and to gene-based reproductive procedures. There is one reason to reject them all, and that is that they do not point to dangers or harms of sufficient seriousness, probability or proximity to justi...

journal_title：Reproductive biomedicine online

authors： Harris J

更新日期：2005-03-01 00:00:00

abstract：:Although numerous methods have been promoted as having an influence on the gender of offspring, most lack credible scientific evidence of effectiveness. Preconception gender selection has an important application in reducing the risk of having children with X-linked disease. A preconception, flow cytometric sperm sort...

journal_title：Reproductive biomedicine online

authors： Schulman JD,Karabinus DS

更新日期：2005-03-01 00:00:00

abstract：:Gonadotrophin-releasing hormone agonist (GnRHa) administration from the mid-luteal phase onwards is considered the gold standard of ovarian stimulation for IVF treatment. It might, however, coincide with an implanting spontaneous pregnancy. Concerns have therefore been raised with regard to the evolution of the result...

journal_title：Reproductive biomedicine online

authors： Papanikolaou EG,Platteau P,Albano C,Kolibianakis E,Devroey P

更新日期：2005-03-01 00:00:00

abstract：:Human embryonic stem (hES) cells are pluripotent cells isolated from early human embryos. They can be grown in vitro and made to differentiate into many different cell types. These properties have suggested that they may be useful in cell replacement therapy for many degenerative diseases. However, if hES cells could ...

journal_title：Reproductive biomedicine online

authors： Pickering SJ,Minger SL,Patel M,Taylor H,Black C,Burns CJ,Ekonomou A,Braude PR

更新日期：2005-03-01 00:00:00

abstract：:GnRH antagonists are used to prevent premature LH surges in assisted reproduction. The pregnancy rates obtained in several studies have been similar to those obtained in the long protocol with gonadotrophin-releasing hormone (GnRH) agonists. However, lower oestrogen serum concentrations have been observed and fewer oo...

journal_title：Reproductive biomedicine online

authors： Engel JB,Riethmüller-Winzen H,Diedrich K

更新日期：2005-02-01 00:00:00

abstract：:Ovarian hyperstimulation syndrome (OHSS) is one of the most important complications of assisted reproductive technologies. Mild OHSS is characterized by ovarian enlargement and abdominal discomfort. In severe cases anasarca, hepatic dysfunction, reduced blood volume, electrolyte imbalance, organ failure and thromboemb...

journal_title：Reproductive biomedicine online

authors： Mercan S,Mercan R,Karamustafalioglu O

更新日期：2005-02-01 00:00:00

abstract：:Clinicians who treat unsuccessful couples despite repeated transfers of good quality embryos face a challenge. Among the various strategies that have been described, embryo transfer at the blastocyst stage has been postulated to improve implantation. A prospective non-randomized analysis was performed in 276 IVF patie...

journal_title：Reproductive biomedicine online

authors： Guerif F,Bidault R,Gasnier O,Couet ML,Gervereau O,Lansac J,Royere D

更新日期：2004-12-01 00:00:00

abstract：:The aim of this review will be to provide a basic understanding of the biophysical processes that accompany the application of cryopreservation in reproductive medicine. The ability to store cells in 'suspended animation' outside the body has become a keystone practice in the development of many modern clinical therap...

journal_title：Reproductive biomedicine online

authors： Fuller B,Paynter S

更新日期：2004-12-01 00:00:00

abstract：:For several years the present authors' team had not been satisfied with the pregnancy rate achieved by their unit, especially in comparison with the results achieved by other teams with a similar population. A quality programme was established, and it was decided to switch from non-stop to intermittent activity. It wa...

journal_title：Reproductive biomedicine online

authors： Frydman N,Fanchin R,Le Dû A,Bourrier MC,Tachdjian G,Frydman R

更新日期：2004-11-01 00:00:00

abstract：:A 40-year-old patient underwent intracytoplasmic sperm injection and assisted hatching, and a single embryo was transferred. Ultrasonography demonstrated a single gestational sac containing monochorionic tri-amniotic pregnancy. Several factors that have been implicated in the aetiology of monozygotic triple pregnancie...

journal_title：Reproductive biomedicine online

authors： Rísquez F,Gil M,D'Ommar G,Poo M,Sosa A,Piras M

更新日期：2004-10-01 00:00:00

abstract：:A cohort follow-up study was designed to compare the efficacy of IVF using frozen donor semen (IVF-D) following previously failed DI cycles (unexplained female infertility) and direct IVF-D treatment because of tubal infertility (control group). The cohort comprised 189 couples initiating IVF-D after previously failed...

journal_title：Reproductive biomedicine online

authors： Guerif F,Saussereau MH,Barthelemy C,Couet ML,Gervereau O,Lansac J,Royere D

更新日期：2004-10-01 00:00:00

abstract：:Accurate assessment of reactive oxygen species (ROS) concentrations may help in the diagnosis of infertility. The chemiluminescence technique, which uses a luminometer to measure ROS, is a common method of assessment. A better understanding of the chemiluminescence technique will allow its proper application in reprod...

journal_title：Reproductive biomedicine online

authors： Agarwal A,Allamaneni SS,Said TM

更新日期：2004-10-01 00:00:00

abstract：:Advances in preimplantation genetic diagnosis (PGD) are occurring worldwide. New clinics specializing in this approach to the control of disease genes or imbalanced chromosome numbers in human preimplantation embryos continue to increase. One exception is Japan, where the Japanese Society of Obstetrics and Gynecology ...

journal_title：Reproductive biomedicine online

authors： Munné S,Cohen J

更新日期：2004-09-01 00:00:00

abstract：:Cryptorchidism is the most frequent congenital anomaly of the urogenital tract in human males. INSL3 and LGR8/GREAT proteins seem to act as ligand and receptor respectively, and to have a role in gubernaculum development involved in testicular descent. Mutations in the INSL3 gene or LGR8/GREAT were found to be associa...

journal_title：Reproductive biomedicine online

authors： Foresta C,Ferlin A

更新日期：2004-09-01 00:00:00

abstract：:The original objection to the paper by Kwong et al. was that the use of an inappropriate (between-pup) estimate of experimental error had exaggerated the importance of the maternal nutrition effect. From the group's most recent response, it has been possible to regenerate the raw data and carry out a further detailed ...

journal_title：Reproductive biomedicine online

authors： Walters E,Edwards RG

更新日期：2004-08-01 00:00:00

abstract：:Polymorphic variants in the phase I enzyme, cytochrome P450 gene, may lead to increased toxification, whereas polymorphisms in the phase II enzyme, glutathione S-transferase genes, may result in impaired detoxification. Alterations in the activities of phase I drug metabolizing enzymes and phase II detoxification enzy...

journal_title：Reproductive biomedicine online

authors： Babu KA,Rao KL,Kanakavalli MK,Suryanarayana VV,Deenadayal M,Singh L

更新日期：2004-08-01 00:00:00

abstract：:In spite of several past attempts at defining the point at which conception can be considered completed, resulting in the formation of an embryo, the existing definitions are still contradictory. In the absence of clear terminology, the application of laws aimed at the protection of early human life may have inadequat...

journal_title：Reproductive biomedicine online

authors： Tesarik J,Greco E

更新日期：2004-07-01 00:00:00

abstract：:Testicular needle aspiration has been proposed as a simple alternative to open biopsy for the diagnosis and treatment of azoospermia. This study describes a new modification of needle aspiration biopsy using an ordinary intravenous catheter to retrieve testicular spermatozoa from patients with obstructive azoospermia,...

journal_title：Reproductive biomedicine online

authors： Fahmy I,Kamal A,Aboulghar M,Mansour R,Serour GI,Shamloul R

更新日期：2004-07-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is associated with increased risk of impaired glucose tolerance and type 2 diabetes. PCOS has been considered as a major risk factor for the development of diabetes, and screening of women with PCOS for glucose intolerance is suggested. Detection of glucose intolerance in PCOS is best ...

journal_title：Reproductive biomedicine online

authors： Yildiz BO,Gedik O

更新日期：2004-06-01 00:00:00

abstract：:The aims of this study were to investigate the relationship between inhibins, activin A and follistatin in first trimester fetal fluids, maternal serum, placenta and decidua, and to investigate if these hormones are present in the circulation of the early second trimester human fetus. Amniotic and coelomic fluid, mate...

journal_title：Reproductive biomedicine online

authors： Muttukrishna S,Jauniaux E,McGarrigle H,Groome N,Rodeck CH

更新日期：2004-06-01 00:00:00

abstract：:Somatic cloning by nuclear transfer returns a differentiated cell to a totipotent stage, a process termed nuclear reprogramming. During this de-differentiation process, genes inactivated during tissue differentiation are re-activated in a temporal and spatial special manner. It is believed that tissue differentiation ...

journal_title：Reproductive biomedicine online

authors： Tian XC

更新日期：2004-05-01 00:00:00

abstract：:A prospective randomized trial was performed to compare post-thaw development of murine blastocysts following programmable rate freezing and two methods of vitrification. Frozen 2-cell murine embryos (n = 429) thawed and cultured for 48 h, were randomly allocated by stage of development into four groups: control (not ...

journal_title：Reproductive biomedicine online

authors： Walker DL,Tummon IS,Hammitt DG,Session DR,Dumesic DA,Thornhill AR

更新日期：2004-05-01 00:00:00

abstract：:The aim of this retrospective study was to determine whether pituitary down-regulation after gonadotrophin-releasing hormone analogue (GnRHa) administration can be accurately predicted by transvaginal ultrasonographic measurement of endometrial thickness in the presence of menstruation. All cycles of an IVF/intracytop...

journal_title：Reproductive biomedicine online

authors： Dogan MM,Uygur D,Alkan RN,Batioglu S,Mollamahmutoglu L

更新日期：2004-05-01 00:00:00

abstract：:Active immunization of proven fertile adult male bonnet monkeys (Macaca radiata) with phage-expressed follicle-stimulating hormone receptor (FSHR)-specific peptides from the extracellular domain resulted in a progressive drop in sperm count with all animals becoming azoospermic by day 100. However, serum testosterone ...

journal_title：Reproductive biomedicine online

authors： Rao AJ,Ramachandra SG,Ramesh V,Couture L,Abdennebi L,Salesse R,Remy JJ

更新日期：2004-04-01 00:00:00

abstract：:Experience with conventional clinical IVF indicates that a first cleavage can occur in the absence of detectable pronuclear formation (so-called silent fertilization). In these instances, the first division is often asymmetrical and delayed when compared with normally fertilized siblings. In this study, DNA configurat...

journal_title：Reproductive biomedicine online

authors： Van Blerkom J,Davis P,Alexander S

更新日期：2004-04-01 00:00:00

abstract：:The Human Fertilisation and Embryology Authority's report on sex selection is criticized because its recommendation to prohibit all techniques for social sexing is based on unsupported allegations. As a body with a scientific status, the Authority should allow the application of some methods of sex selection for non-m...

journal_title：Reproductive biomedicine online

authors： Pennings G

更新日期：2004-03-01 00:00:00

abstract：:This study aims to compare a psychological evaluation test to classical psychoanalysis in infertile women. Two hundred women were submitted to the Psychological Evaluation Test (PET). The sum of the scores for the responses ranged from 15 to 60 points, with scores >/=30 points being defined as 'psycho-emotional maladj...

journal_title：Reproductive biomedicine online

authors： Franco JG Jr,Silva PG,Achê RS,Baruffi RR,Mauri AL,Petersen CG,Felipe V,Vagnini L,Oliveira JB

更新日期：2004-01-01 00:00:00